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Researchers used Truveta Data from over 40,000 patients to assess whether newer GLP-1 RA medications semaglutide and tirzepatide, commonly known by brand names Ozempic, Wegovy, Mounjaro, and Zepbound are associated with lower risks of emergency department visits and hospitalizations related to alcohol use

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Thus, an Y1R agonist and an Y2R antagonist would be expected to have similar anxiolytic effects as acute alcohol in the CeA (Figure 6)

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Karantysh, G