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Suzhou-based Innovent Biologics saw its obesity drug, Mazdutide, approved by Chinese regulators last yearand according to a 2025 report released by LEK Consulting, China has more than 60 obesity drug candidates under development that are set to compete with those produced in the United States

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These findings define a previously unrecognized microbiotabutyratemTORC1ISR axis as a central driver of PBAT-MPs-induced brain injury, and suggest that restoring butyrate signaling or targeting the downstream mTORC1ISR pathway may represent a translatable strategy for preventing BMP-related neurodegeneration