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Metabolic diseases and protein homeostasis Metabolic syndrome (MetS) and its associated disorders, such as type 2 diabetes mellitus (T2DM), obesity, non-alcoholic fatty liver disease (NAFLD), and CVDs, represent a significant global health burden

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SM, KN, HS, and SK provided materials and technical advice

A study showed that repeated and prolonged alcohol administration increases depressive and anxious behaviors in mice, which are associated with reduced iron homeostasis and synaptic plasticity [23]

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In addition, research has shown that feeding male Wistar rats a high-sucrose diet for 4 weeks significantly increases serum triglyceride and cholesterol levels