agonistas del receptor glp-1 duales de receptores y GIP en la diabetes tipo 2: mecanismos de acción GLP-1 receptor agonists (GLP-1RAs): cardiovascular

A variety of drugs have been reported to alleviate renal tissue damage by reducing ROS and inflammation, most of which is achieved through the Nrf2/HO-1 signaling pathway (Table 2)

A once-weekly injectable glucose-dependent insulinotropic polypeptide/GLP-1 dual agonist conferred up to 14.7% weight loss at 13 weeks for adults with overweight or obesity, according to findings from the VENTURE trial published in Obesity

These effects of leptin are dramatically plastic, reversible, and regionally specific in the human brain morphology (London et al., 2011)

Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue

The constant mental noise around food fades

Why Im cautious: The human efficacy story is not in the same league as GLP-1 evidence