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Von Willebrand Disease (VWD) illustrated how real-world data can bridge the gap between symptoms and diagnosis, helping clinicians identify diagnostic delays, quantify disease burden, understand patient journeys, and generate evidence that supports more timely, personalized, and patient-centered care

Future such studies will benefit from more comprehensive evaluation of the brain congruent with the periphery, wherein the contributions of sex and other key parameters (treatment dose, concentration, and frequency) are queried at multiple life stages

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