In addition, a meta-analysis of 1193 patients with baseline SGLT2i use in AMPLITUDE-O and Harmony Outcomes revealed an HR for MACE of 0.78 (95% CI 0.491.24) with SGLT2is and 0.77 (95% CI 0.680.87) without SGLT2is ( P -value for interaction 0.95), and an HR for HHF of 0.34 (95% CI 0.120.96) with SGLT2is and 0.72 (95% CI 0.550.92) without SGLT2is ( P -value for interaction 0.18) [48]
SNAC: sodium N -[8-(2-hydroxybenzoyl)amino] caprylate
Until more evidence is available, approved treatments remain the safest and most reliable option for eligible patients
Emerging research is raising new concerns about the effects of these drugs on muscle and bone health
Relieve GLP-1-related bowel irregularity and gastrointestinal discomfort like occasional gas, bloating, constipation and diarrhea
Hormones generally fall into 3 catigories, peptide hormones, steroid hormones and amine hormones