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DNA methylation that results from obesity creates an epigenetic memory that persists even after weight loss, prolonging chronic inflammation and increasing cancer risk

doi: 10.3390/toxins9040132 105 KimSSRuizVECarrollJDMossSF

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While the medication has demonstrated substantial weight loss in clinical trials, it is important to understand that tirzepatide is not specifically a "fat-burning" agent in the traditional sense, but rather works through appetite suppression and metabolic regulation