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Carnitine has been supplemented in a great variety of patients, such as inborn errors in the carnitine system, mitochondrial beta oxidation, mitochondrial acyl-CoA-linked enzymes, oxidative phosphorylation [35,84], in cardiovascular diseases [85], AIDS [60], in diabetes mellitus [86], chronic fatigue syndrome [87], chemotherapy- [88] and interferon-a- [89] induced fatigue, children with ADHD [90]
Hasegawa and M
Key areas of investigation include: Gastrointestinal : Demonstrated protection against NSAID-induced ulcers, inflammatory bowel disease models, and esophageal damage in multiple animal studies Musculoskeletal : Accelerated healing of transected Achilles tendons, quadriceps muscles, and medial collateral ligaments in rat models Neurological : Neuroprotective effects in models of traumatic brain injury, nerve crush injury, and dopaminergic system damage Organ protection : Hepatoprotective, cardioprotective, and nephroprotective effects demonstrated in various toxicity models The primary limitation is that all evidence comes from animal models
It is well known that giving up alcohol is not an easy decision and often requires professional support
Jiayu H, Jiaying L, Hanke Z, et al
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