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From a regulatory perspective, exosome-based products represent a new class of biologic therapy, and navigating the approval pathways will require robust data on their biodistribution, potential immunogenicity, and long-term safety, establishing clear guidelines that are still under development

27 237253 10.1016/0166-3542(95)00008-A [DOI] [PubMed] [Google Scholar] Pineda-Molina E., Klatt P., Vazquez J., Marina A., Garcia De Lacoba M., Perez-Sala D., et al

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AOD-9604 does not cause water loss or glycogen depletion the way GLP-1 agonists do, so there is no early "whoosh" effect

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