It is only available on prescription, and people must meet eligibility criteria concerning their BMI and weight-related health conditions
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Research comparing mice treated with GLP-1 medications versus those on calorie restriction with similar weight loss showed the GLP-1 group had substantially greater reductions in liver fat 19
doi:10.1016/S0196-9781(97)00001-6
Both trials suggest maintenance strategies, such as lower-dose injections or oral therapies, could offer patients more flexible, potentially more convenient options for sustaining weight loss after intensive treatment
In addition to direct actions, pancreatic -cells can also be affected by paracrine actions that promote insulin production and release, thereby indirectly inhibiting glucagon secretion (Saltiel and Kahn, 2001