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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 10% by weight of the povidone

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Contraindications and clinical precautions include: Medullary thyroid carcinoma (MTC): Cagrilintide is contraindicated in individuals with a personal or family history of MTC due to its structural similarity to calcitonin, which may theoretically influence C-cell activity