As of the time of writing, retatrutide has not been granted a marketing authorisation by the MHRA or the EMA, and therefore there is no official MHRA safety guidance or Yellow Card reporting data specific to this compound in the public domain
So, do GLP-1 patches work, and are they available
In a statement published alongside the results, Amgen said: Weight loss had not plateaued by 52 weeks, indicating the potential for further weight reduction. It added that improvements were recorded across other cardiometabolic measures, including waist circumference, blood pressure, high-sensitivity C-reactive protein (hs-CRP) and select lipid parameters
A Phase 2 trial published in the New England Journal of Medicine (2023) reported significant weight reduction with retatrutide over 48 weeks, and further trials are registered on ClinicalTrials
Adverse effects also differ
It is more like turning down the volume on hunger while helping the body handle calories differently