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While physiological levels of ROS are required in the normal transition between wound healing phases, as previously described, an overproduction of ROS has deleterious effects and can hinder wound healing 159

Adjuvant therapies that target a known pathogenic variant (e.g., KIT ) (under clinical evaluation)

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Ultimately, prospective studies evaluating bone outcomes with different GLP-1 RAs in this population, incorporating standardized DXA assessments and fracture surveillance, are needed to establish evidence-based skeletal health guidelines

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On control plates the biomass of glutathione mutants was not different from the WT, except for zir1 (Fig