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This heart protection works mainly through SIRT1 activation, as SIRT1 knockout mice don't show these benefits [7]

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Early studies have demonstrated stable expression of VDR in normal human epidermal melanocytes (NHEMs), with its levels regulated by 1,25(OH)D, suggesting that active Vitamin D may exert distinct physiological roles in pigment cells via the VDR signaling pathway [131, 132]

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Influence of positive aspects of dementia caregiving on caregivers wellbeing: A systematic review