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The limited secondary structure in these peptides reduces the hydrophobic hot spots that mediate benzyl alcohol destabilization in globular proteins

IV infusions, however, must be administered in a clinic

Cold chain storage requirements, syringe handling, injection site rotation, and the discomfort of subcutaneous administration all add friction to research protocols

Access and affordability: The high cost of GLP-1 drugs remains a significant hurdle for patients and payers