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Storage summary: Refrigerate (not freeze) immediately after reconstitution

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(2) Downstream protection with cartilage-building substrates (e.g., collagen peptides, vitamin D) to enhance matrix integrity (11, 12)

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We assessed cytochrome P450 3A4 (CYP3A4) activity in the derived smHLCs (under all conditions), by analysing the ability of the cells to induce CYP3A4 upon challenge with the proto-typical inducer Rifampicin