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10.1158/1940-6207.CAPR-10-0098 29 CarrozzaM

European Archives of Psychiatry and Clinical Neuroscience 259 :284-292

Sequence: trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH

Hawaii Med J

For skin health, it inhibits the key enzyme in melanin production, leading to more even skin tone

This broad transcriptomic influence spans pathways involved in collagen synthesis, metalloproteinase regulation, antioxidant response, and copper-dependent enzyme activation, making GHK-Cu one of the most comprehensively profiled peptides in in vitro research