If you want the biology the literature predicts, you need a delivery method that bypasses the stratum corneum
albicans protein QS: Quorum sensing PIA: Polysaccharide intercellular adhesin PPI: Proton pump inhibitors AhR: Aryl hydrocarbon receptor ILC3s: Group 3 ILCs Treg: Regulatory T CRAMP: Cathelicidin-related antimicrobial peptides FMT: Fecal microbiota transplant CDI: C
This system involves enzymes such as CPTI, CACT and CPTII, and its activity can vary with fasting, exercise or carbohydrate availability, so simplistic interpretations should be avoided
That matters because protein provides amino acids that help produce neurotransmitters that help regulate mood, including serotonin
Semaglutide has two amino acid substitutions compared to human GLP-1 (Aib(8), Arg(34)) and is derivatized at lysine 26
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