Future studies should validate our findings in genetic models to determine whether the observed gut-brain interactions are generalizable across ASD subtypes
57 NaderN.ChrousosG
In particular, one randomized, double-blind, placebo-controlled clinical trial demonstrated that daily oral administration of equal-lower doses (5 g/day) of l-ARG for a shorter period (1 month) compared to the current study significantly increased IIEF-6 score in 34 diabetic middle-aged men affected by mildmoderate ED of unknown etiology [27]
[DOI] [PubMed] [Google Scholar] 15.Bellenger CR, Beck JA
2016;6(1) doi: 10.1038/srep33251.33251 [DOI] [PMC free article] [PubMed] [Google Scholar] 35.Zhao L., Chen Y., Xia F., et al
Immediate Mitochondrial and Neurological Oxidative Protection Hydrogen water offers unique advantages in providing immediate protection to cellular regions where GR activity may be naturally limited or insufficient: Blood-brain barrier penetration : While GR is expressed in brain tissue, hydrogen molecules readily cross the blood-brain barrier, providing antioxidant protection regardless of endogenous GR status
