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Efficacy, tolerability and pharmacokinetics of survodutide, a glucagon/GLP-1 receptor dual agonist, in cirrhosis

The schedule is daily for weeks 14, five times a week for weeks 58, then two or three times a week for ongoing maintenance

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10 mg Vials (Ipamorelin, 10 mg each) 8 weeks 2 vials 12 weeks 23 vials 16 weeks 3 vials 5 mg Vials (Ipamorelin, 5 mg each) 8 weeks 2 vials 12 weeks 4 vials 16 weeks 5 vials Insulin Syringes (U-100) Per week: 7 syringes (1/day) 8 weeks: 56 syringes 12 weeks: 84 syringes 16 weeks: 112 syringes Bacteriostatic Water (10 mL bottles) Use ~3.0 mL per vial for reconstitution