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This expanded approval is based on results from the pivotal FLOW phase 3b clinical trial, which demonstrated that once-weekly semaglutide led to a statistically significant 24% reduction in the risk of kidney disease progression, kidney failure, and cardiovascular death compared to placebo, when added to standard care

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Coronal cryosections of 50 m thickness at 1 mm intervals were obtained and stained with cresyl violet

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