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Similarly, WHO also stressed concerns that these false medications can "cause toxic reactions." "They are neither approved nor controlled by competent authorities and may have been produced in unhygienic conditions by unqualified personnel, contain unknow impurities and can be contaminated with bacteria," WHO said.

SRD5A1 is predominantly expressed in skin and annexes 23,25,26

The threshold at which this association has been observed is serum levels over 813 pg/mL (600 pmol/L)

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