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Wu Z, Li L, Yang Y, Hu P, Li Y, Yang SY, et al

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In the semaglutide group, DEGs were primarily involved in lipid metabolism, fatty acid oxidation, ATP biosynthesis, and oxidoreductase activity

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Because this was an observational study in a specific clinical population, randomized clinical trials are needed before GLP-1 medications can be recommended for treating addiction. However, the team believes their results are promising and plan to continue studying GLP-1s effect on substance abuse