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To help illustrate the therapeutic significance and developmental advancement of these natural chemicals, Table 2 highlights their molecular targets, experimental models used, clinical status, and potential future research avenues

Different studies revealed that SIRT1 has a protective effect against neurodegeneration and neuronal injury (Di et al

Many studies indicate that specific foods can exacerbate or alleviate the symptoms of this disease (216, 220)

Growth hormone-releasing peptide (GHRP-6) is a synthetic hexapeptide that specifically stimulates the secretion of growth hormone by pituitary somatotrophs

They found that the knockdown of endogenous IRS-1 significantly decreased PI3K/AKT signaling and this effect was similarly shown in BC cells with miR-148a or miR-152 overexpression leading to the inhibition of cell proliferation