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This persistent pain is attributed to a combination of inflammatory and non-inflammatory mechanisms, with peripheral and central sensitization being implicated as key contributors (Biddle and Sofat 2020)

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RSPO2 enhances canonical Wnt signaling to confer stemness-associated traits to susceptible pancreatic cancer cells

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Common precipitants include fever, exercise, warm temperatures, spicy foods, and alcohol

Using a combination of mouse genetics, functional cell biology and pharmacology, we unraveled the function of glutathione in keratinocytes and its cross-talk with other antioxidant defense systems