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Some individuals may feel slight tightness or mild irritation at the injection site, which usually resolves quickly

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Compounding pharmacies in the United States previously prepared BPC-157 for clinical use, but the FDA issued guidance restricting its inclusion in compounded preparations due to its lack of an approved new drug application (NDA)

For example, cystic fibrosis patients suffer from severe gram-negative bacterial infections and are commonly prescribed the aminoglycoside antibiotics amikacin or tobramycin, despite as high as a 14% incidence of hearing loss (Cheng et al., 2007

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