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6D) showed that YTHDF1 knockdown significantly elevated intracellular energy metabolism, whereas SLC7A5 overexpression significantly decreased ATP levels, suggesting its detrimental effect on mitochondrial function

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Marchetti P, Decaudin D, Macho A, Zamzami N, Hirsch T, Susin SA et al

The former study was conducted in an area with sufficient Se and therefore failed to show a short-term therapeutic effect of Se in hyperthyroidism