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In general: 48 weeks: Improvements in overall skin glow and radiance may become noticeable

Clinical data show that in 24 weeks, over 85% improved mood and sleep

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For many drug effects, the response increases with increase in dose, with low sub-therapeutic doses giving an inadequate response, therapeutic doses giving the desired response, but very high doses giving an excessive response that can be regarded as a form of toxicity (response 1 in Fig

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