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3 AshiuchiM.MisonoH

Because Dihexa initiates synaptic structural changes that take hours to days to fully developrather than producing immediate neurotransmitter effectssplitting the daily dose provides no pharmacodynamic advantage

10.1038/s41392-021-00831-w 57

Thioctic Acid will break down when exposed to sunlight

Dams JK, Eiken HG, Oie E, Bjerkeli V, Yndestad A, Ueland T, Tonnessen T, Geiran OR, Aass H, Simonsen S, Christensen G, Froland SS, Attramadal H, Gullestad L, Aukrust P

Depression has a very high rate of suicides (Bains and Abdijadid 2021)