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Take 5 capsules daily with a sufficient amount of water (2 capsules in the morning, 2 capsules in the afternoon, 1 capsule in the evening) with meals, preferably not exceeding the recommended daily dose

Nat Rev Endocrinol (2011) 8(3):16071

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Thus, impaired oxidative metabolism results in decreased energy production, increased cortical excitability, and CSD, which in turn causes migraines when mitochondrial damage or dysfunction occurs in the brain

Oral supplements are also available, but injections are more effective as they bypass the digestive system and directly enter the bloodstream

King, S