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Theyre not going to have the same effects as drugs such as Ozempic, which stay in the body at a lot higher levels. Notably, semaglutide drugswhich mimic GLP-1bind to GLP-1 receptors and activate them but have a much longer duration of action due to their structural modifications, which make them less susceptible to enzymatic degradation, he points out

But the preclinical cancer data is remarkable

Potential potency variations between batches

To view a copy of this licence, visit About this article Cite this article Wajdlich, M., Nowicki, M

Khanijow V, Prakash P, Emsellem HA, et al

NICE guidance and NHS resources provide a robust framework for sustainable weight management that does not rely on investigational pharmacology