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Other classes of non-enzymatic components include vitamins (e.g., ascorbic acid, -tocopherol), enzymatic cofactors (e.g., Coenzyme Q10), nitrogen compounds (e.g., uric acid), carotenoids (e.g., -carotene, lutein), and minerals (e.g., zinc, selenium)

Funding No funding or sponsorship was received for this study or the publication of this article

Although ROS generated under physiological conditions are not harmful, and likely play a signaling role, toxic or pathological conditions that lead to an impairment of mitochondrial function can increase the release of ROS

10.1126/sciadv.abe0083 176 ZaissM

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