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By JJ Luime, BW Koes, IJM Hendriksen, A Burdorf, AP Verhagen, HS Miedema, JAN Verhaar | Year: 2004 | Scandinavian Journal of Rheumatology | Volume: 33 | Issue: 2 | Page: 73-81 | Digital Object Identifier: 10.1080/03009740310004667 -------- Disclaimer: The information in this blog post about treating shoulder pain is provided for general informational purposes only and may not reflect current medical thinking or practices

2 Epigenetic allostasis model As an inescapable factor of the natural world, stress plays a pivotal role in the adaptive and maladaptive responses to the environment through epigenetic mechanisms [1, 18]

Do redox-modulating therapies (e.g., thiamine, CoQ10, NRF2 activators, molecular hydrogen), when compared to placebo or standard care, improve pain, fatigue, sleep, or oxidative stress markers in FM