Key points GLP-1 is a hormone that increases insulin release and prevents the release of too much glucagon, helping manage blood glucose levels in individuals with type 2 diabetes GLP-1 receptor agonists, such as liraglutide and semaglutide, effectively reduce blood glucose levels Semaglutide is more effective than liraglutide at reducing blood sugar levels Tirzepatide is a newer GLP-1 receptor agonist that also mimics the actions of another hormone called GIP, which can also reduce blood sugar levels A randomised controlled trial showed that tirzepatide led to more significant blood sugar reductions than semaglutide across three doses Tirzepatide may be more effective than semaglutide at higher doses, but this needs further investigation Liraglutide and semaglutide are available in the UK and the US, while tirzepatide is only available in the US but is likely to be approved in the UK soon

Cuando el semaglutide se inyecta directamente desde el refrigerador, el lquido fro puede causar mayor incomodidad al entrar en el tejido subcutneo
Choosing between them: Your primary goal (blood sugar vs weight management), medical history, and insurance coverage often guide the decision
Real-world results vary but tend to align with trial ranges when patients maintain consistent dosing
the study enforces the evidence that use of GLP-1 RA can reduce the weight gain attributable to insulin in this population
When it's time for your first dose, a myAster nurse comes to your home to give the injection and show you exactly how it's done, so you feel confident doing it yourself from then on