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In one example, GSH-driven nanoparticle disintegration releases indomethacin to inhibit PTGS2 while reducing Pt 4 + to cytotoxic Pt 2 + , thereby amplifying cisplatin-induced pyroptosis in pancreatic cancer 218
Weight loss was an observed side effect during early trials for these medications
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Scientific References Chelakkot C, et al
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Early intervention with an FDA-approved weight loss drug program can mitigate these risks before they exacerbate
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