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Patients should not discontinue Wegovy due to yeast infections without discussing this with the prescribing clinician, as the metabolic benefits of continued treatment typically outweigh the inconvenience of manageable infections

It upregulates vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF), stimulates angiogenesis to improve blood supply to damaged tissue, and enhances collagen synthesis at injury sites

Grading quality of evidence and strength of recommendations

PMID 26631183 Krivic A, Anic T, et al

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For researchers studying melanocortin biology, the more informative comparison is between MT-2, PT-141, and Melanotan-1 (afamelanotide), which is a linear alpha-MSH analog with selective MC1R agonism approved by the EMA for erythropoietic protoporphyria