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Compared with GFR, cystatin C has a stronger association with death from cardiovascular or any other cause in those with advanced CKD (Menon 2007

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Furthermore, supplementation with LC has a positive impact on numerous essential pathways involved in pathological skeletal muscle loss, which might explain at least some of the anti-catabolic benefits and improvements in fatigue-related metrics seen in chronic illness people who received it (Montesano et al., 2015, Ringseis et al., 2013)

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