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Other drugs in the broader liver-disease pipeline have shown that improvements in liver fat and improvements in fibrosis can actually be separate

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Kislinger T, Fu C, Huber B, Qu W, Taguchi A, Du Yan S, Hofmann M, Yan SF, Pischetsrieder M, Stern D, et al: N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression

Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts