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Yes, many integrative veterinarians use GHK-Cu as part of a joint support protocol to help reduce inflammation and aid cartilage repair

This is not unusual and reflects the complex interplay of slowed gastric emptying (which promotes constipation) and altered intestinal motility (which can trigger diarrhea)

Mixing Best Practices Avoid shaking or vortexing (can denature peptides)

Alpha-lipoic acid is available in a wide range of doses

The MINE 1 creators then totaled each dog's scores for the four echo measurements to arrive at what they call a "severity classification", in Table 2 (below)

Berberine, particularly in high doses, can also cause cramping, diarrhea, and flatulence