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To acquire comprehensive data on vitamin D signaling, Dimitrov and colleagues analyzed raw data from 94 gene expression profiles (80 from humans, 14 from mice) regulated by calcitriol or its analogs [147]

Rheumatoid arthritis: evolving recognition of a common disease

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In line with our results, it has been found that metformin inhibits islet -cell dedifferentiation by decreasing C3, Nga3, and Oct4 while increasing Pdx1 and MafA expression, with C3 promoting dedifferentiation through the Wnt/-catenin pathway [79]

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In another clinical trial conducted by Yahyapoor et al., supplementation of critically ill patients with the same dose of L-carnitine improved the serum ALB concentration and decreased inflammation in the intervention group [44]