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As with other incretin-based therapies, the most commonly reported side effects include nausea, vomiting, diarrhea and constipation, particularly during dose escalation

JAMA 316 , 500508 (2016)

The Aib residue at position 2 and the fatty acid modification both confer resistance to the primary degradation enzymes (DPP-4 and neprilysin), extending the metabolic half-life

But at higher concentrations like 20mg/mL, 1 unit of dead space equals 200mcg, and 5 draws waste 1,000mcg (1mg), which is 5% of a 20mg vial

Generally safe, side effect is usually constipation (which you may already have)

However, as with all other types of drugs, these medicines are not free from possible side effects