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Clinical relevance depends on the specific medication, patient profile, and treatment setting

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E., Christopoulos, A., Miller, L

GSPT1 degradation has emerged as a promising therapeutic strategy in oncology, but its essential role in normal cellular proliferation creates a narrow therapeutic window

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Advanced / Aggressive Protocol (2 mL = ~10.0 mg/mL) Note: The 12 mg dose represents the highest dose tested in Phase 2 trials [3] [4] , producing maximum weight-loss efficacy (~24% body weight at 48 weeks)