microdosing a glp-1 is popular, but there's little evidence it works There isn't enough data to

it involves priming your body and your environment

Exendin-4, a new peptide from Heloderma suspectum venom, potentiates cholecystokinin-induced amylase release from rat pancreatic acini

The supramammillary nucleus, located in the hypothalamus, is a new candidate that appears to be responsible for GLP-1 mediated anxiety effects because selective activation of GLP-1Rs in this nucleus by exendin-4 resulted in intensified anxiety-like behavior both in male and female rats

Secondly, GLP-1 receptor agonists carry important safety considerations including risk of pancreatitis, gallbladder disease, and potential thyroid C-cell tumours (based on rodent studies, though human relevance remains uncertain)

They dont fit the typical prescribing criteria for GLP-1snamely, having diabetes or being obese

doi: 10.1016/j.ebiom.2021.103242 11 CaoCYangSZhouZ