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Occludin monoclonal antibody (batch number 66378) and STAT3 polyclonal antibody (batch number 10253-2-AP) were obtained from Proteintech

Typically administered orally in tablet form, Polypodium extract serves as an oral supplement, often preferred over topical creams due to its enhanced efficacy

ROS-induced apoptosis also explains the beneficial effect of two analogs of nuclear receptor ligands in several types of cancer: 2-methoxyestradiol, a 17-estradiol metabolite, and N-(4-hydroxyphenyl) retinamide, a synthetic analog of retinoic acid, have been shown to induce PCD in neuroblastoma and lung cancer cells, respectively 104,105

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Lamm, V., Huang, K., Deng, R., Cao, S., Wang, M., Soleymanjahi, S., Promlek, T., Rodgers, R., Davis, D., Nix, D., Oliva Escudero, G., Xie, Y., Chen, C.-H., Gremida, A., Rood, R