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Very dark Six to twelve months

Drug (in blood) Metabolite(in blood) Metabolite in urine and bile t1/2 = ln 2 * V / CL where: V is the volume of distribution CL is the clearance of the molecule Common features of Phase II metabolism ii

UGTs are membranebound enzymes similarly to cytochromes P450 with subcellular localization in the endoplasmic reticulum (ER)

These similarities include: Support antioxidant defense systems: Both NAC and glutathione help protect your cells from oxidative stress

Njalsson, R., Ristoff, E., Carlsson, K., Winkler, A., Larsson, A

In this situation, the body is exposed to the harmful effects of these metabolites