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Sustained microglial activation leads to the release of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which exacerbate neuronal injury and amplify amyloid and tau pathology (Kaur et al., 2019)
CNS symptoms Brainfog and sensory overload responded best to treatment with an SSRI
however, the ferroptosis stress is alleviated with supraphysiological cystine supplement, though under which the TSS pathway is nonfunctional
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