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The starting dose is 0.6mg daily for one week, which can be increased up to 1.2mg daily for the second week

In both in vitro (human neuroblastoma SH-SY5Y cells) and in vivo (PSAPP-Tg: double transgenic mice expressing chimeric mouse/human amyloid precursor protein and mutant human presenilin 1 directed to CNS neurons), catalpol alleviates Alzheimers disease progression by promoting the level of miR-138-5p in exosomes secreted by neural stem cells (Meng S

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Most research protocols use 12 mg per injection dose, so a 10 mg vial reconstituted with 2 mL of bacteriostatic water yields 5 mg/mL