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The hearts of animals perfused with caffeine and taurine showed shortened repolarisation times and refractory periods on the ECG trace, followed by ventricular arrhythmias, confirming the potential arrhythmogenic effect of these substances

The primary enzymes/genes of glutathione system (Figure 1) are -glutamylcystiene synthetase ( gshA ), glutathione synthetase ( gshB ), glutathione reductase ( gshR/gor ), and glutathione peroxidase ( gpo )