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Other medications may impair tissue repair, deplete nutrients, disrupt sleep, or increase systemic inflammation, which can make pain more persistent despite temporary symptom relief

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The FDA classifies it as a Category 2 bulk drug substance, noting potential safety concerns in unregulated compounding

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This approach aligns with the growing recognition that the future of pain management lies not in blocking pain signals indefinitely, but in actually healing the underlying pathology

2016;11(6):e0157602