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Representative data of two experiments (n = 3, two-sided unpaired t-test)
An enzyme called dipeptidyl peptidase-4 (DPP-4) rapidly metabolizes GLP-1 and GIP, rendering them inactive
Sections were incubated with 5% normal rat serum followed by further incubation
What deeply worries clinical experts like Bayat is that patients, driven by societal pressure and social media trends, are bypassing the vital safeguards built into South Africas medical infrastructure
Of note, all AE outcomes were severe, including dulaglutide: ketoacidosis (n = 58), marasmus (n = 17), hyperglycaemic hyperosmolar nonketotic syndrome (n = 12), diabetic ketosis (n = 4)